University Profile Database

Dr. Fu Cheng (George) Liang

Email Addresses
fucheng.liang@msutexas.edu
My Websites
  • Chemistry
    Assistant Professor

    Office Location
    Bolin Hall 307G
    Phone
    Voice: (940) 397-4472
  •   Semester Course # Section Course Name Location Days / Times
    Details Spring 2021 4253 Biochemistry Bolin Hall
    Details Spring 2021 1303 GENERAL-ORGANIC-BIOL CHEMISTRY Bolin Hall
    Details Spring 2021 1141 General Chemistry lab Bolin Hall
    Details Fall 2020 4243 Biochemistry Bolin Hall
    Details Fall 2020 4242 Biochemistry lab Bolin Hall
    Details Fall 2020 1303 GENERAL-ORGANIC-BIOL CHEMISTRY Bolin Hall
    Details Fall 2017 4243 Biochemistry Bolin Hall
    Details Fall 2017 4242 Biochemistry lab Bolin Hall
    Details Fall 2017 1303 GENERAL-ORGANIC-BIOL CHEMISTRY Bolin Hall
  • Institution Degree Graduation Date
    National Chung Cheng University BS 2000-6-30 0:0:0
    National Taiwan University MS 2002-6-30 0:0:0
    Texas A&M Health Science Center PhD 2011-6-30 0:0:0
  • Institution Position Start Date End Date
    Academia Sinica Research Assistant 2002-July 2004-June
    California Institute of Technology Post-doctoral Scholar 2011-July 2017-June
  • Publication: 

    1. Alex Siegel, Camille Z. McAvoy, Vinh Lam, Fu-Cheng Liang, Gerard Kroon, Emily Miaou, Patrick Griffin, Peter E. Wright, Shu-ou Shan (2020) Journal of Molecular Biology, 432, 166708, “A disorder-to-order transition activates an ATP-Independent Membrane Protein Chaperone.”
    2. Peng Wang, Fu-Cheng Liang, Daniel Wittmann, Alex Siegel, Shu-ou Shan, Bernhard Grimm (2018) Proceedings of the National Academy of Sciences of the United States of America115(15), E3588-E3596 “Chloroplast SRP43 acts as chaperone for glutamyl-tRNA reductase, the rate-limiting enzyme in tetrapyrrole biosynthesis.”
    3. Fu-Cheng Liang, Gerard J. Kroon, Camille McAvoy, Chris Chi, Peter Wright and Shu-ou Shan (2016) Proceedings of the National Academy of Sciences of the United States of America, 113(12), E1615-E1624 “Conformational Dynamics of a Membrane Protein Chaperone Enables Spatially-regulated Substrate Capture and Release.”
    4. Peera Jaru-Ampornpan, Fu-Cheng Liang, Alex Nisthal, Thang X. Nguyen, Steven Mayo, and Shu-ou Shan (2013) The Journal of Biological Chemistry, 288, 13431-13445 “Mechanism of an ATP-independent Protein Disaggregase. II. Distinct Molecular Interactions Drive Multiple Steps during Aggregate Disassembly.”
    5. Fu-Cheng Liang, Umesh K. Bageshwar and Siegfried M. Musser (2012) The Journal of Biological Chemistry, 287, 12703-12714 “Position-dependent Effects of Polylysine on Sec Protein Transport.”
    6. Fu-Cheng Liang, Umesh K. Bageshwar and Siegfried M. Musser (2009) Molecular Biology of the Cell, 20, 4256-4266 “Bacterial Sec Protein Transport is Rate-Limited by Precursor Length: A Single Turnover Study.”
    7. Umesh K. Bageshwar, Neal Whitaker, Fu-Cheng Liang and Siegfried M. Musser (2009) Molecular Microbiology, 74(1), 209-226 “Interconvertibility of Lipid- and Translocon- Bound Forms of the Bacterial Tat Precursor pre-Sufl.”
    8. Marianne M. Lee, Clara E. Isaza, James D. White, Rita P.-Y. Chen, George F.-C. Liang, Hannah T.-F. He, Sunney I. Chan, Michael K. Chan (2009) Proteins: Structure, Function, and Bioinformatics, 77(3), 647-657 “Insight into the substrate length restriction of M32 carboxypeptidases: Characterization of two distinct subfamilies.”
    9. Rita P.-Y. Chen, Fu-Cheng Liang, Chung-Tien Lee, Rosa Zerella and Sunney I. Chan (2008) Journal of the Chinese Chemical Society 55(4), 772-781Contributions of a Surface Hydrophobic Cluster to the Folding and Structural Stability of Ubiquitin.”
    10. Clara E. Isaza, Xuejun Zhong, Lucia E. Rosas, James D. White, Rita P.-Y. Chen, George F.-C. Liang, Sunney I. Chan, Abhay R. Satoskar and Michael K. Chan (2008) Biochem Biophys Res Commun. 373(1), 25-29 “A Proposed role for Leishmania major Carboxypeptidase in Peptide Catabolism.”
    11. Fu-Cheng Liang, Rita P.-Y. Chen, Chun-Cheng Lin, Kuo-Ting Huang and Sunney I. Chan (2006) Biochem Biophys Res Commun. 342(2), 482-488 “Tuning the Conformation Properties of a Peptide by Glycosylation and Phosphorylation.”

    Research interested:

    • Protein targeting and transport across cell membrane
    • Protein folding and misfolding or amyloid formation
    • Membrane protein biogenesis
    • Protein structural and functional studies by NMR and fluorescence spectroscopy